Appropriateness of fresh-frozen plasma usage in hospital settings: a meta-analysis of the impact of organizational interventions

Transfusions of fresh-frozen plasma (FFP) are a worldwide ever-growing practice. The most advanced health care organizations, to guarantee high-quality standards of interventions and safe procedures, should disseminate scientific evidence for promoting the appropriateness of transfusions and reducing avoidable risks.

STUDY DESIGN AND METHODS:

We carried out a systematic review of scientific literature searching for studies focused on the implementation of different strategy of organizational interventions aimed at improving clinicians' practice.

RESULTS:

Of 915 studies, 10 articles were included in our meta-analysis of risk of inappropriate transfusion after the implementation of an organizational intervention. The risk ratio of inappropriate transfusions before organizational interventions was 2.02 (95% confidence interval, 1.44-2.84) compared with after interventions.

CONCLUSION:

The organizational interventions showed a positive impact on the reduction of rates of inappropriate FFP transfusion episodes.

 

OverigEducational gatheringsEducational literature distributionsFeedbackOrganizational interventionsBehandeling zonder medicatie

 

Auteurs

Damiani G
Pinnarelli L
Sommella L
Farelli V
Mele L
Menichella G
Ricciardi W

 

Link

https://www.ncbi.nlm.nih.gov/pubmed/19719469